TIGIT Chimeric Recombinant Rabbit Monoclonal Antibody (1B4), Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen MA548199

Product Code. 17971671

Description

Specificity: This antibody is specific for murine TIGIT.

Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.

Specifications

• Antigen: TIGIT Chimeric
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% ProClin 300
• Gene Accession No.: P86176
• Gene Symbols: TIGIT
• Immunogen: This antibody was raised by immunising TIGIT-/- mice with recombinant murine TIGIT tetramers.
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Form: Liquid

• Applications: ELISA, Flow Cytometry, Inhibition Assays, Western Blot
• Clone: 1B4
• Conjugate: Unconjugated
• Gene: TIGIT
• Gene Alias: ENSMUSG00000071552; T cell immunoreceptor with Ig and ITIM domains; T-cell immunoreceptor with Ig and ITIM domains; TIGIT; V-set and immunoglobulin domain containing 9; V-set and immunoglobulin domain-containing protein 9; V-set and transmembrane domain containing 3; V-set and transmembrane domain-containing protein 3; VSIG9; VSTM3; Washington University cell adhesion molecule; WUCAM
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 100043314
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Isotype: IgG λ