THZ1 Hydrochloride, MedChemExpress

Product Code.	Quantity	unitSize
16440698	5 mg	5mg
16434137	50 mg	50mg
16407976	100 mg	100mg
16458248	10 mg	10mg

Product Code. 16440698

Brand: Medchem Express HY80013A

Description

MedChemExpress THZ1 Hydrochloride is a selective and potent covalent CDK7 inhibitor with an IC50 of 3.2 nM. THZ1 Hydrochloride also inhibits the closely related kinases CDK12 and CDK13 and downregulates MYC expression.

THZ1 Hydrochloride is a selective and potent covalent CDK7 inhibitor with an IC50 of 3.2 nM. THZ1 Hydrochloride also inhibits the closely related kinases CDK12 and CDK13 and downregulates MYC expression.

Specifications

• Chemical Name or Material: THZ1 Hydrochloride
• Physical Form: Solid
• Color: Yellow
• Quantity: 5 mg
• Purity Grade Notes: Research
• Molecular Formula: C₃₁H₂₉Cl₂N₇O₂
• For Use With (Application): Cancer-Kinase/protease
• Solubility Information: DMSO : 22.5 mg/mL (37.34 mM; Need ultrasonic and warming) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
• SMILES: ClC1=CN=C(NC2=CC(NC(C3=CC=C(NC(/C=C/CN(C)C)=O)C=C3)=O)=CC=C2)N=C1C4=CNC5=CC=CC=C54.Cl
• Molecular Weight (g/mol): 602.51
• Formula Weight: 602.51
• Percent Purity: 98.14%
• Grade: Research

Research purposes only