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Description
Mainly used in forming hybrid cell lines using HAT (hypoxanthine-aminopterin-thymidine) medium to give rise to monoclonal antibodies. Also used in HT and HAT cocktails for hybridoma fusion, selection and cloning.
Deoxythymidine can be phosphorylated with one, two or three phosphoric acid groups, creating respectively dTMP, dTDP or dTTP (deoxythymidine mono-, di-, or triphosphate). The stability of deoxythymidine under standard temperature and pressure (STP) is very high. Thymidine is listed as a chemical teratogen.
Specifications
Specifications
| Melting Point | 185°C to 191°C |
| Quantity | 1 g |
| Solubility Information | Soluble in water, methanol, hot alcohol, hot acetone, hot ethyl acetate pyridine, glacial acetic acid and HCl (20mg/mL, clear, colorless solution); sparingly soluble in hot chloroform. |
| Optical Rotation | 17.5–19.5° (c=1, water) |
| Formula Weight | 242.2 |
| Percent Purity | >99.9% |
| Physical Form | Powder |
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