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Invitrogen™ Thromboxane synthase Polyclonal Antibody

Description
Peptide sequence: GYEIITNTLS FATYLLATNP DCQEKLLREV DVFKEKHMAP EFCSLEEGLP Sequence homology: Cow: 86%; Dog: 93%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 79%; Pig: 100%; Rabbit: 86%; Rat: 86%.
Thromboxane synthase encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Specifications
Specifications
| Antigen | Thromboxane synthase |
| Applications | Western Blot |
| Classification | Polyclonal |
| Concentration | 0.5 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 2% sucrose and 0.09% sodium azide |
| Gene | TBXAS1 |
| Gene Accession No. | P24557 |
| Gene Alias | BDPLT14; CYP5; Cyp5a1; cytochrome P450 5A1; cytochrome P450, family 5, subfamily A, polypeptide 1; FLJ52771; GHOSAL; platelet, cytochrome P450, subfamily V; similar to Thromboxane-A synthase (TXA synthase) (TXS); Tbxas1; THAS; ThromboxA ane synthase 1; thromboxane A synthase 1; thromboxane A synthase 1 (platelet); thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A); thromboxane A synthase 1, platelet; thromboxane synthase; thromboxane-A synthase; TS; TXA synthase; TXAS; TXS |
| Gene Symbols | TBXAS1 |
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