Invitrogen™ Thimet Oligopeptidase Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA583269

Product Code. 16380225

Description

Immunogen sequence: AACAGDMADA ASPCSVVNDL RWDLSAQQIE ERTRELIEQT KRVYDQVGTQ EFEDVSYEST LKA Highest antigen sequence indentity to the following orthologs: Mouse - 78%, Rat - 76%.

A steady-state level of amyloid beta-peptide (Abeta) represents a balance between its biosynthesis from the amyloid precursor protein (APP) through the action of the beta and gamma-secretases and its catabolism by a variety of proteolytic enzymes. Thimet Oligopeptidase (THOP1) has been shown to promote A-beta degradation. It has also been shown to play a role in antigen presentation, metabolism of neuropeptides under 20 amino acids, and cytoplasmic peptide degradation.

Specifications

• Antigen: Thimet Oligopeptidase
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Thop1
• Gene Alias: AI131655; AI327041; EC 3.4.24; EC 3.4.24.15; endo-oligopeptidase A; Endopeptidase 24.15; EP24.15; MEPD_HUMAN; metalloendopeptidase; MP78; PZ-peptidase; soluble metallo-endopeptidase; Thimet oligopeptidase; thimet oligopeptidase 1; Thop1; TOP
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7064
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P52888
• Gene Symbols: Thop1
• Immunogen: Recombinant protein corresponding to Human THOP1. Recombinant protein control fragment (Product #RP-104658).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG