Thiazole, 99%

Product Code.	Quantity	unitSize
11332377	5 g	5g
11322377	1 g	1g

Product Code. 11332377 Supplier Thermo Scientific Alfa Aesar Supplier No. L09970.06

Description

CAS: 288-47-1 | C3H3NS | 85.12 g/mol

Thiazole is used as a flavoring agent and in the preparation of dyes and rubber accelerators. It serves as a component of the vitamin thiamine (B1). It acts as a protected formyl group used in natural product synthesis. It reacts with alkyl lithium and Grignard’s reagent to prepare organometallic complexes. It is involved in the electrophilic aromatic substitution and nucleophilic aromatic substitution at C-5 and C-2 positions respectively. Further, it undergoes alkylation reaction to get thiazolium cation, which is used as a catalyst in the Stetter reaction and the Benzoin condensation. In addition to this, it is involved in the preparation of alagebrium.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Thiazole is used as a flavoring agent and in the preparation of dyes and rubber accelerators. It serves as a component of the vitamin thiamine (B1). It acts as a protected formyl group used in natural product synthesis. It reacts with alkyl lithium and Grignard’s reagent to prepare organometallic complexes. It is involved in the electrophilic aromatic substitution and nucleophilic aromatic substitution at C-5 and C-2 positions respectively. Further, it undergoes alkylation reaction to get thiazolium cation, which is used as a catalyst in the Stetter reaction and the Benzoin condensation. In addition to this, it is involved in the preparation of alagebrium.

Solubility
Soluble in ethanol and ether. Slightly soluble in water.

Notes
Air and light sensitive. Incompatible with acids, acid chlorides, acid anhydrides, strong oxidizing agents and carbon dioxide.

Specifications

Chemical Identifiers

• CAS: 288-47-1
• Molecular Formula: C3H3NS
• Molecular Weight (g/mol): 85.12
• MDL Number: MFCD00005315
• InChI Key: FZWLAAWBMGSTSO-UHFFFAOYSA-N
• Synonym: thiazole, thiazol, unii-320rcw8pef, fema no. 3615, ccris 3205, 320rcw8pef, lom, racemic thiazole, 5h-thiazol-1-ium
• PubChem CID: 9256
• ChEBI: CHEBI:43732
• IUPAC Name: 1,3-thiazole
• SMILES: S1C=CN=C1

• Melting Point: -33°C
• Density: 1.2
• Boiling Point: 117°C to 118°C
• Flash Point: 22°C (71°F)
• Odor: Unpleasant
• Refractive Index: 1.539
• Quantity: 5 g
• UN Number: UN1993
• Beilstein: 103852
• Sensitivity: Air and light sensitive
• Merck Index: 14,9307
• Solubility Information: Soluble in ethanol and ether. Slightly soluble in water.
• Formula Weight: 85.13
• Percent Purity: 99%
• Chemical Name or Material: Thiazole

Safety and Handling

SDS

RUO – Research Use Only