Invitrogen™ Human TIMP1 Recombinant Protein

Recombinant Protein

Brand:  Invitrogen™ RP75735

Product Code. 11549051

Description

TIMP1 (human) Recombinant Protein, RP-75735, from Invitrogen.

TIMP1 (metalloproteinase inhibitor 1) is a metalloproteinase inhibitor that functions by forms one-to-one complexes with target metallproteinases, such as collagenases, and irreversible inactivates them by binding to their catalytic zinc cofactor. TIMP1 acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP14, and MMP16. It also functions as a growth factor that regulates cell differenation, migration, and cell death. TIMP1 activates cellular signaling cascades via CD63 and ITGB1. This product contains a purified 184 amino acid fragment (aa24-207) corresponding to the mature TIMP-1 protein with an N-terminal hexahistidine tag. This product may be used as a positive control in many immunological assays. This protein has a molecular weight of ∽25.21 kDa.

Specifications

• Accession Number: P01033
• For Use With (Application): Control, Western Blot
• Gene ID (Entrez): 7076
• pH Range: 4.8
• Source: E. coli
• Storage Requirements: -20°C, Avoid Freeze/Thaw Cycles
• Gene Alias: Tissue Inhibitor of Metalloproteinase 1,TIMP1
• Gene Symbol: TIMP1
• Conjugate: Unconjugated
• Species: E. coli
• Form: Liquid
• Purity or Quality Grade: purified

• Concentration: 0.31mg/mL
• Formulation: 0.025M acetic acid with 50% glycerol and no preservative; pH 4.8
• Name: Human TIMP1
• Quantity: 1mg
• Immunogen: N/A
• Regulatory Status: RUO
• Common Name: Human TIMP1
• Specific Reactivity: Human
• Cross Reactivity: Hu
• Recombinant: Recombinant
• Protein Subtype: Recombinant