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Invitrogen™ Human PRDX2, Recombinant Protein

Product Code. 10223810
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Quantity:
0.2 mg
Unit Size:
0.2 unit
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Product Code. 10223810

Brand: Invitrogen™ LFP0007

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This item is not returnable. View return policy

Description

Recombinant Protein

Peroxiredoxin 2 (Hu) Recombinant Protein, LF-P0007, from Invitrogen.

Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, particularly amino-terminal region containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20 - 30 kilodalton in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol. This protein corresponds to human Peroxiredoxin II (1-198 aa), which has a molecular weight of 22 kDa. Specific activity: 1.2 U/mg, where one unit will cause the oxidation of 1 umol of NADPH at 25°C at pH 7.5. Purity: >95% by SDS-PAGE. Reconstitution Instructions: Add 200uL of distilled water to 0.2mg of lyophilized product to bring final concentration to 1.0mg/mL. After reconstitution, store at -80°C and avoid freeze and thaw cycles.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P32119
Concentration 1mg/mL
For Use With (Application) Control
Formulation 20mM HEPES with 10% glycerol and no preservative; pH 7.5
Gene ID (Entrez) 7001
Name Human PRDX2
pH Range 7.5
Quantity 0.2 mg
Source E. coli
Storage Requirements -80°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Common Name Human PRDX2
Gene Symbol PRDX2
Specific Reactivity Human
Conjugate Unconjugated
Cross Reactivity Hu
Species E. coli
Recombinant Recombinant
Form Lyophilized
Protein Subtype Recombinant
Purity or Quality Grade purified
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in vitro research only.

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