Invitrogen™ Human Monoamine Oxidase B Recombinant Protein

Product Code.	Quantity	unitSize
11568981	100 μg	100µg

Product Code. 11568981 Supplier Invitrogen™ Supplier No. RP75660

Description

Recombinant Protein

This product contains purified recombinant human Monoamine Oxidase B protein with an N-terminal hexahistidine tag. This product may be used as a positive control in many immunological assays.

MAOB (Monoamine Oxidase B), also called MAO, BRAIN, AMINE OXIDASE (FLAVIN-CONTAINING) B, is a protein that in humans is encoded by the MAOB gene. MAOB is a member of the flavin monoamine oxidase family. And it is mapped on Xp11.3. MAOB catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. Like MAOA, it also degrades dopamine. MAO-B is involved in the breakdown of dopamine, a neurotransmitter implicated in reinforcing and motivating behaviors as well as movement. MAO-B inhibition is, therefore, associated with enhanced activity of dopamine, as well as with decreased production of hydrogen peroxide, a source of reactive oxygen species.

Specifications

• Accession Number: P27338
• Concentration: 0.268 mg/mL
• For Use With (Application): Control, Western Blot
• Formulation: 25 mM tris HCl with 0.01 mM EDTA, 50% glycerol, 75 mM NaCl and no preservative; pH 8
• Gene ID (Entrez): 4129
• Molecular Weight (g/mol): 59.84 kDa
• Name: Human Monoamine Oxidase B
• pH Range: 8
• Quantity: 100 μg
• Source: E. coli
• Immunogen: N/A
• Regulatory Status: RUO
• Gene Alias: 6330414K01Rik; adrenalin oxidase; amine oxidase [flavin-containing] B; HGNC:6834; MAO b; MAO, brain; MAO, platelet; Maob; MAO-B; MGC26382; monoamine oxidase B; monoamine oxidase type B; monoamine oxidase-B; RP1-201D17__B0.1; tyramine oxidase
• Common Name: MAOB
• Gene Symbol: MAOB
• Conjugate: Unconjugated
• Species: E. coli
• Recombinant: Recombinant
• Protein Tag: His-tag
• Sequence: Amino acids Ser2- Val489 containing an N-terminal His-tag
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Liquid
• Protein Subtype: Recombinant
• Purity or Quality Grade: >95%, by SDS-PAGE under reducing conditions