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Invitrogen™ Human GPD2 Recombinant Protein
Description
This product contains purified recombinant human mitochondiral Glycerol-3-PO4 Dehydrogenase protein with an N-terminal hexahistidine tag. This product may be used as a positive control in many immunological assays.
Mitochondrial glycerophosphate dehydrogenase (EC 1. 1. 99. 5), or GPD2, is located on the outer surface of the inner mitochondrial membrane and catalyzes the unidirectional conversion of glycerol-3-phosphate (G-3-P) to dihydroxyacetone phosphate (DHAP) with concomitant reduction of the enzyme-bound FAD. Together with a cytosolic NAD-linked GPD (GPD1; MIM 138420), GPD2 forms the glycerol phosphate shuttle, which uses the interconversion of G-3-P and DHAP to transfer reducing equivalents into mitochondria, resulting in the reoxidation of NADH formed during glycolysis.
Specifications
Specifications
| Accession Number | P43304 |
| Concentration | 0.095 mg/mL |
| For Use With (Application) | Control, Western Blot |
| Formulation | 20 mM tris HCl with 1 mM EDTA, 50% glycerol and no preservative; pH 8 |
| Gene ID (Entrez) | 2820 |
| Name | Human GPD2 |
| Quantity | 100 μg |
| Source | E. coli |
| Immunogen | N/A |
| Regulatory Status | RUO |
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