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Invitrogen™ Human INHA Recombinant Protein

Product Code. 11588951
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Quantity:
10 μg
Unit Size:
10µg
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11588951 10 μg 10µg
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Product Code. 11588951 Supplier Invitrogen™ Supplier No. RP75632

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Description

Recombinant Protein

RP-75632 contains a purified 134 amino acid fragment (aa233-366) corresponding to the mature Inhibin alpha subunit protein with an N-terminal hexahistidine tag. RP-75632 may be used as a positive control in Western blot assays.

The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.
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Specifications

Accession Number P05111
Concentration 0.05 mg/mL
For Use With (Application) Control, Western Blot
Formulation Laemmli with no preservative; pH 6.8
Gene ID (Entrez) 3623
Molecular Weight (g/mol) 19.2 kDa
Name Human INHA
pH Range 6.8
Quantity 10 μg
Source E. coli
Regulatory Status RUO
Gene Alias A inhibin subunit; A-inhibin subunit; AW555078; IHA; Inha; inhibin; inhibin alpha; inhibin alpha chain; inhibin alpha subunit
Common Name INHA
Gene Symbol INHA
Conjugate Unconjugated
Species E. coli
Recombinant Recombinant
Protein Tag His-tag
Sequence Amino acids Ser233- Ile366 containing an N-terminal His-tag
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Protein Subtype Recombinant
Purity or Quality Grade >95%, by SDS-PAGE under reducing conditions
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