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Invitrogen™ Human GDNF Recombinant Protein
Recombinant Protein
Brand: Invitrogen™ RP8602
Code : LE
Additional Details : Weight : 0.01000kg
Description
GDNF (human) Recombinant Protein, RP-8602, from Invitrogen.
Glial Cell Line-Derived Neurotrophic Factor (GDNF) is a neurotrophic factor that is closely related to other neurotrophic factors, such as Neurturin, Persephin, and Artemin, by a common structural feature called the cysteine-knot. GDNF signals through a multicomponent system of receptors that includes RET and GFRalpha1-4, to promote dopamine uptake, survival and differentiation of neurons. Recombinant human GDNF is a non-glycosylated homodimer, containing two 135 amino acid chains, with a total molecular weight of 30.4 kDa. Purity is typically greater than 98% and endotoxin level less than 1 EU/ug. The expected biological activity (ED50) is determined by the dose-dependent proliferation of C6 cells and is typically 0.5-5 ug/mL. The specific activity of this protein is 2x10^3 units/mg. Reconstitute using sterile water at 0.1mg/mL and centrifuge prior to opening vial. Gently pipet solution down the sides of the vial. DO NOT VORTEX sample. Store reconstituted material at -20°C and add 0.1% BSA for additional stability. Amino acid sequence: MSPDKQMAVL PRRERNRQAA AANPENSRGK GRRGQRGKNR GCVLTAIHLN VTDLGLGYET KEELIFRYCS GSCDAAETTY DKILKNLSRN RRLVSDKVGQ ACCRPIAFDD DLSFLDDNLV YHILRKHSAK RCGCI.Specifications
P39905 | |
Control | |
2668 | |
Human Glial Cell Derived Neurotrophic Factor (GDNF) | |
10μg | |
-20°C, Avoid Freeze/Thaw Cycles | |
H-GDNF | |
GDNF | |
Unconjugated | |
E. coli | |
Lyophilized | |
purified |
0.1mg/mL | |
0.01M citric acid with 0.1M NaCl and no preservative; pH 4.0 | |
30.36 | |
4.0 | |
E. coli | |
RUO | |
Human Glial Cell Derived Neurotrophic Factor (GDNF) | |
Human | |
Hu | |
Recombinant | |
Recombinant |
in vitro research purpose only.