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Human Glial Cell Derived Neurotrophic Factor (GDNF), Recombinant Protein, Invitrogen™

Recombinant Protein

Brand:  Invitrogen RP8602

Code : LE

Additional Details : Weight : 0.01000kg

Product Code. 11549121

  • £226.00 / 10µg

EU Stock 3

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Description

Description

Glial Cell Line-Derived Neurotrophic Factor (GDNF) is a neurotrophic factor that is closely related to other neurotrophic factors, such as Neurturin, Persephin, and Artemin, by a common structural feature called the cysteine-knot. GDNF signals through a multicomponent system of receptors that includes RET and GFRalpha1-4, to promote dopamine uptake, survival and differentiation of neurons. Recombinant human GDNF is a non-glycosylated homodimer, containing two 135 amino acid chains, with a total molecular weight of 30.4 kDa. Purity is typically greater than 98% and endotoxin level less than 1 EU/ug. The expected biological activity (ED50) is determined by the dose-dependent proliferation of C6 cells and is typically 0.5-5 ug/mL. The specific activity of this protein is 2x10^3 units/mg. Reconstitute using sterile water at 0.1mg/mL and centrifuge prior to opening vial. Gently pipet solution down the sides of the vial. DO NOT VORTEX sample. Store reconstituted material at -20°C and add 0.1% BSA for additional stability. Amino acid sequence: MSPDKQMAVL PRRERNRQAA AANPENSRGK GRRGQRGKNR GCVLTAIHLN VTDLGLGYET KEELIFRYCS GSCDAAETTY DKILKNLSRN RRLVSDKVGQ ACCRPIAFDD DLSFLDDNLV YHILRKHSAK RCGCI.
Specifications

Specifications

P39905
Control
Control
0.01M citric acid with 0.1M NaCl and no preservative; pH 4.0
30.36
4.0
10μg
-20°C, Avoid Freeze/Thaw Cycles
H-GDNF
GDNF
Unlabeled
E. coli
Recombinant
0.1mg/mL
Lyophilized
2668
Human Glial Cell Derived Neurotrophic Factor (GDNF)
purified
E. coli
RUO
Human Glial Cell Derived Neurotrophic Factor (GDNF)
Human
Hu
Recombinant
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in vitro research purpose only.