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Invitrogen™ Human CCL2 (MCP-1) Recombinant Protein
Description
This product contains purified recombinant human CCL2 protein with an N-terminal hexahistidine tag. This product may be used as a positive control in many immunological assays.
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
Specifications
Specifications
| Accession Number | P13500 |
| Concentration | 0.225 mg/mL |
| For Use With (Application) | Control, Western Blot |
| Formulation | 20 mM tris HCl with 50% glycerol and no preservative; pH 8 |
| Gene ID (Entrez) | 6347 |
| Name | Human CCL2 (MCP-1) |
| Quantity | 1 mg |
| Source | E. coli |
| Immunogen | N/A |
| Regulatory Status | RUO |
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