Thermo Scientific™ MSTFA and MSTFA + 1% TMCS Silylation Reagent

Product Code.	Standard Components	Quantity	unitSize
11507680	MSTFA	100 mL	Each
11587670	MSTFA	10 g	Each
11786957	MSTFA	10 x 1 mL ampules	Pack of 10
11567851	MSTFA + 1% TMCS	10 x 1 mL ampules	Pack of 10
11597670	MSTFA	25 mL	25mL

Product Code. 11507680 Supplier Thermo Scientific™ Supplier No. TS48914

Description

Offer maximum volatility with the Thermo Scientific™ MSTFA and MSTFA + 1% TMCS Silylation Reagent.

Use Thermo Scientific™ MSTFA and MSTFA + 1% TMCS Silylation Reagent for GC analyses of early eluting compounds that would otherwise be obscured in the chromatogram. MSTFA, the most volatile TMS-amide available, and its byproduct N-methyltrifluoroacetamide typically elute with the solvent front, allowing TMS derivatives of small molecules to be analyzed. Addition of Thermo Scientific™ TMCS aids derivatization of amides, secondary amines, and hindered hydroxyls not derivatized by MSTFA alone.

• Trimethylsilyl donor strength comparable to BSA and BSTFA
• Reacts to replace labile hydrogens on a wide range of polar compounds with a Si(CH₃)₃ group
• Used to prepare volatile and thermally stable derivatives for GC and MS
• Volatile byproduct, N-methyltrifluoroacetamide, has an even lower retention time than MSTFA
• Often TMS derivatives of small molecules can be analyzed when derivatized with MSTFA because the byproducts and the reagent itself usually elute with the solvent front
• Addition of Thermo Scientfic TMCS aids derivatization of amides, secondary amines and hindered hydroxyls not derivatized by MSTFA alone

Specifications

• For Use With: GC/MS
• Hazards: Flammable, Irritant
• Standard Concentration: 98 to 100%
• Storage: 2°C to 8°C
• Quantity: 100 mL
• Standard Components: MSTFA

Safety and Handling

Product Identifier

• MSTFA, 100 mL. N-Methyl-N-TMS-Trifluoro

Signal Word

• Warning

Hazard Category

• Flammable liquid Category 3
• Serious eye damage/eye irritation Category 2
• Specific target organ toxicity Category 3
• Skin corrosion/irritation Category 2

Hazard Statement

• H226-Flammable liquid and vapour.
• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H335-May cause respiratory irritation.

Precautionary Statement

• P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
• P264-Wash thoroughly after handling.
• P271-Use only outdoors or in a well-ventilated area.
• P370+P378-In case of fire: Use to extinguish.
• P302+P352-IF ON SKIN: Wash with plenty of water/.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
• P403+P233-Store in a well-ventilated place. Keep container tightly closed.
• P403+P235-Store in a well-ventilated place. Keep cool.
• P501-Dispose of contents/container to .

For Research Use Only. Not for use in diagnostic procedures.