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Thermo Scientific™ TheraPure™ PAC-rA Phosphoramidite, serum vial bottle

Product Code. 17907182 Shop All Thermo Scientific Products
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Product Code. 17907182 Supplier Thermo Scientific™ Supplier No. 27180302

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Description

PAC-rA CEP is a phosphoramidite containing 5' DMT and the nucleoside adenosine (A) with Phenoxyacetyl (PAC) base protection, for use in oligonucleotide synthesis.

PAC-rA CEP is a phosphoramidite containing 5' DMT and the nucleoside adenosine (A) with Phenoxyacetyl (PAC) base protection, for use in oligonucleotide synthesis. The UltraMILD monomers - phenoxyacetyl (PAC)-dA, acetyl (Ac)-dC, and iso-propyl-phenoxyacetyl (iPr-PAC)-dG - were developed to alleviate the problem of modifiers and labels not withstanding prolonged exposure to strongly alkaline deprotection conditions. Cleavage and deprotection can be achieved in 4 hours at room temperature with 0.05M potassium carbonate in methanol. The TheraPure trademark denotes our highest level of phosphoramidite purity, developed with the greatest stringency of high definition analytics and tightly controlled impurity profiles and, therefore, ideal for any therapeutic application. This product is supplied in a 20 mL Amber bottle with a Serum Vial neck style, which is compatible with most ABI Systems|AKTA Systems of oligonucleotide synthesizers.

Features:
• Full chemical name: 5'-O-(4,4'-Dimethoxytrityl)-N6-phenoxyacetyl-2'-O-TBDMSi-adenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula: C54H68N7O9PSi
• Base: rA
• Base Protection: PAC
• Formula weight: 1018.2 g/mol
• CAS number: 121058-86-4
• HPLC Purity: ≥99%
• 31P NMR Purity: ≥99%; Sum of non-primary peaks in 140-152 ppm range: ≤0.5%; No single PIII impurity (140-152 ppm) >0.3%

TRUSTED_SUSTAINABILITY

Specifications

For Use With (Equipment) AKTA Synthesizers, Applied Biosystems Synthesizers
Product Type PAC-rA CEP
Content And Storage Store in freezer (at or below -20°C).
Nucleoside Type Adenosine (A)
Reagent Features Fast deprotection
Shipping Condition Room Temperature
Purity 99%
Quantity 1 g
Reagent Type Phosphoramidite
Grade TheraPure™
Nucleic Acid Type RNA
Product Line TheraPure
Form Powder
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For Research Use Only. Not for use in diagnostic procedures.

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