Invitrogen™ THEM2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA520777

Product Code. 12858922

Description

A suggested positive control is HepG2 cell lysate. PA5-20777 can be used with blocking peptide PEP-0891.

THEM2, also known as ACOT13, belongs to the hotdog-fold superfamily and possesses thioesterase activity, with greater activity observed with longer chain acyl-CoAs such as myristoyl- and palmitoyl-CoA. THEM2 is highly expressed in several tissues such as heart, kidney, liver and brain and has been shown to be co-localized with beta-tubulin on microtubules. THEM2 interacts with StarD, a protein that plays a key role in fatty acid metabolism, and the addition of StarD to THEM2 increased its catalytic activity, suggesting that THEM2 plays a significant role in the metabolism of fatty acids. At least two isoforms of THEM2 are known to exist.

Specifications

• Antigen: THEM2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ACOT13
• Gene Alias: 0610006O17Rik; Acot13; Acyl-CoA thioesterase 13; acyl-coenzyme A thioesterase 13; Acyl-coenzyme A thioesterase 13, N-terminally processed; HT012; hypothalamus protein HT012; PNAS-27; Them2; thioesterase superfamily member 2
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 291135, 55856, 66834
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q9CQR4, Q9NPJ3
• Gene Symbols: ACOT13
• Immunogen: A 17 amino acid peptide near the carboxy terminus of human THEM2.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG