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Invitrogen™ THEM2 Polyclonal Antibody

Product Code. 12858922
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Quantity:
100 μg
Unit Size:
100µg
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12858922 100 μg 100µg
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Product Code. 12858922 Supplier Invitrogen™ Supplier No. PA520777

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Description

Rabbit Polyclonal Antibody

A suggested positive control is HepG2 cell lysate. PA5-20777 can be used with blocking peptide PEP-0891.

THEM2, also known as ACOT13, belongs to the hotdog-fold superfamily and possesses thioesterase activity, with greater activity observed with longer chain acyl-CoAs such as myristoyl- and palmitoyl-CoA. THEM2 is highly expressed in several tissues such as heart, kidney, liver and brain and has been shown to be co-localized with beta-tubulin on microtubules. THEM2 interacts with StarD, a protein that plays a key role in fatty acid metabolism, and the addition of StarD to THEM2 increased its catalytic activity, suggesting that THEM2 plays a significant role in the metabolism of fatty acids. At least two isoforms of THEM2 are known to exist.
TRUSTED_SUSTAINABILITY

Specifications

Antigen THEM2
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene ACOT13
Gene Accession No. Q9CQR4, Q9NPJ3
Gene Alias 0610006O17Rik; Acot13; Acyl-CoA thioesterase 13; acyl-coenzyme A thioesterase 13; Acyl-coenzyme A thioesterase 13, N-terminally processed; HT012; hypothalamus protein HT012; PNAS-27; Them2; thioesterase superfamily member 2
Gene Symbols ACOT13
Host Species Rabbit
Immunogen A 17 amino acid peptide near the carboxy terminus of human THEM2.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 291135, 55856, 66834
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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