Thapsigargin, 95%

Artikelnummer.	Quantity	unitSize
15435169	1 mg	1mg
15425169	5 mg	5mg
15445169	10 mg	10mg

Artikelnummer. 15435169 Lieferant Thermo Scientific Alfa Aesar Lieferanten-Nr. J62866.M^

Beschreibung

CAS: 67526-95-8 | C34H50O12 | 650.76 g/mol

Thapsigargin- induces down regulation of the EGF receptor is independent of protein kinase C activation. It is also used as an inducer of stored Ca2+ release.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Thapsigargin- induces down regulation of the EGF receptor is independent of protein kinase C activation. It is also used as an inducer of stored Ca2+ release.

Solubility
Soluble in DMSO (20 mg/ml), ethanol (20 mg/ml), and acetone.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C.

Spezifikation

Chemische Identifikatoren

• CAS: 67526-95-8
• Molecular Formula: C34H50O12
• Molecular Weight (g/mol): 650.76
• MDL Number: MFCD00083511
• InChI Key: IXFPJGBNCFXKPI-FSIHEZPISA-N
• PubChem CID: 126969181
• SMILES: CCCCCCCC(=O)O[C@@H]1[C@@H](OC(=O)C(\C)=C/C)C(C)=C2[C@@H]3OC(=O)[C@@](C)(O)[C@@]3(O)[C@H](C[C@](C)(OC(C)=O)[C@@H]12)OC(=O)CCC

• Color: White
• Quantity: 1 mg
• Sensitivity: Light sensitive
• Merck Index: 14,9272
• Synonym: thapsigargin, unii-z96bq26rzd, z96bq26rzd, chembl96926, octanoic acid 3s-3alpha, 3abeta, 4alpha, 6beta, 6abeta, 7beta, 8alpha z , 9balpha-6-acetyloxy-2,3,-3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-2-methyl-1-oxo-2-butenyl oxy-2-oxo-4-1-oxobutoxy-azuleno 4,5-b furan-7-yl ester, octanoic acid, 6-acetyloxy-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-2-methyl-1-oxo-2-butenyl oxy-2-oxo-4-1-oxobutoxy azuleno 4,5-b furan-7-yl ester, 3s-3alpha,3abeta,4alpha,6beta,6abeta,7beta,8alpha z ,9balpha, tg1, --thapsigargin, octanoic acid 3s-3alpha, 3abeta, 4alpha, 6beta,6abeta, 7beta, 8alpha z , 9balpha-6-acetyloxy-2,3,-3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-2-methyl-1-oxo-2-butenyl oxy-2-oxo-4-1-oxobutoxy-azuleno 4,5-b furan-7-yl ester, octanoic acid 3s-3alpha, 3abeta, 4alpha,6beta, 6abeta, 7beta, 8alpha z , 9balpha-6-acetyloxy-2,3,-3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-2-methyl-1-oxo-2-butenyl oxy-2-oxo-4-1-oxobutoxy-azuleno 4,5-b furan-7-yl ester
• Solubility Information: Soluble in DMSO (20mg/ml),ethanol (20mg/ml),and acetone.
• IUPAC Name: [(3S,3aR,4S,6S,6aS,7S,8S,9bR)-6-acetyloxy-4-butanoyloxy-3,3a-dihydroxy-3,6,9-trimethyl-8-(2-methylbut-2-enoyloxy)-2-oxo-4,5,6a,7,8,9b-hexahydroazuleno[4,5-b]furan-7-yl] octanoate
• Formula Weight: 650.75
• Percent Purity: 95%
• Physical Form: Solid Film
• Chemical Name or Material: Thapsigargin

Sicherheit und Handhabung

Produktidentifikator

• Thapsigargin

Signalwort

• Danger

Gefahrenkategorie

• Serious eye damage/eye irritation Category 2
• Respiratory sensitiser Category 1
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Gefahrenhinweis

• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.
• H335-May cause respiratory irritation.

Sicherheitshinweis

• P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P284-[In case of inadequate ventilation] wear respiratory protection.
• P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• P332+P313-If skin irritation occurs: Get medical advice/attention.
• P337+P313-If eye irritation persists: Get medical advice/attention.

Ergänzende Informationen

• MIXTURE LIST-Contain: Thapsigargin

Sicherheitsdatenblatt (SDS)

RUO – Research Use Only