Tocris Bioscience™ Thalidomide 5'-amine-PEG3-amine

Product Code. 18768546

Brand: Tocris Bioscience™ 7737/25

Description

Cereblon ligand with PEG linker and terminal amine for onward chemistry

Thalidomide 5'-amine-PEG3-amine is a functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a PEG3 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Specifications

• Chemical Name or Material: 5-[(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride
• Quantity: 25 mg
• Target: CRBN
• Molecular Formula: C₂₁H₂₈N₄O₇.HCl
• Purity: 0.95