Invitrogen™ TGR5 Monoclonal Antibody (409522)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA561413

Product Code. 30535739

Description

Reconstitute at 0.5 mg/mL in sterile PBS.

This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein.

Specifications

• Antigen: TGR5
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with trehalose and no preservative
• Gene Accession No.: Q8TDU6
• Gene Symbols: GPBAR1
• Immunogen: NS0 mouse myeloma cell line transfected with human TGR5/GPBAR1, Met1-Asn330.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Flow Cytometry
• Clone: 409522
• Conjugate: Unconjugated
• Gene: GPBAR1
• Gene Alias: BG37; C16DUPq36.3; DUP7q36.3; G protein-coupled bile acid receptor 1; G protein-coupled receptor; G protein-coupled receptor TGR5; Gpbar1; GPCR; GPCR HBG37; GPCR19; GPR131; G-protein coupled bile acid receptor 1; G-protein coupled bile acid receptor BG37; G-protein coupled receptor GPCR19; hBG37; Helodermin-preferring VIP receptor; hGPCR19; M-BAR; membrane bile acid receptor; membrane-type receptor for bile acids; PACAP type III receptor; PACAP-R3; PACAP-R-3; pituitary adenylate cyclase-activating polypeptide type III receptor; Tgr5; vasoactive intestinal peptide receptor 2; vasoactive intestinal polypeptide receptor 2; vasopressive intestinal peptide receptor 2; VIP and PACAP receptor 2; VIP receptor subtype 2; Vip2; VIP2R; VIPR2; VIP-R-2; VPAC2; VPAC2 receptor; VPAC2R; VPCAP2R
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 151306
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Lyophilized