Invitrogen™ TGFBR3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA582343

Product Code. 16369304

Description

Immunogen sequence: GYSGMDVTLL DPTCKAKMNG THFVLESPLN GCGTRPRWSA LDGVVYYNSI VIQVPALGDS SGWPDGYEDL ESGDNGFPGD MDEGDASLFT RPEIVVFNCS LQQVRNPSSF QEQPHGNITF NMELYNTDLF Highest antigen sequence indentity to the following orthologs: Rat - 78%, Mouse - 78%.

This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Specifications

• Antigen: TGFBR3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TGFBR3
• Gene Alias: 1110036H20Rik; AU015626; AW215636; betaglycan; betaglycan proteoglycan; BGCAN; OTTHUMP00000011787; TBRIII; tgf beta receptor 3; TGF-beta receptor type 3; TGF-beta receptor type III; Tgfbr3; TGFR-3; transforming growth factor beta receptor 3; transforming growth factor beta receptor III; Transforming growth factor beta receptor type 3; transforming growth factor, beta receptor 3; transforming growth factor, beta receptor III
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7049
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q03167
• Gene Symbols: TGFBR3
• Immunogen: Recombinant protein corresponding to Human TGFBR3. Recombinant protein control fragment (Product #RP-88952).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG