TGFBR3 Monoclonal Antibody (1C5H11), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA517187

Product Code. 15368150

Description

MA5-17187 targets TGFBR3 in indirect ELISA, WB applications and shows reactivity with Human and Mouse samples. The MA5-17187 immunogen is purified recombinant fragment of human TGFBR3 (amino acids: 147-328 ) expressed in E. Coli. MA5-17187 detects TGFBR3 which has a predicted molecular weight of approximately 93.4kDa.

This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Specifications

• Antigen: TGFBR3
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: O88393, Q03167
• Gene Symbols: TGFBR3
• Immunogen: Purified recombinant fragment of human TGFBR3 (amino acids: 147-328 ) expressed in E. Coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Western Blot
• Clone: 1C5H11
• Conjugate: Unconjugated
• Gene: TGFBR3
• Gene Alias: 1110036H20Rik; AU015626; AW215636; betaglycan; betaglycan proteoglycan; BGCAN; OTTHUMP00000011787; TBRIII; tgf beta receptor 3; TGF-beta receptor type 3; TGF-beta receptor type III; Tgfbr3; TGFR-3; transforming growth factor beta receptor 3; transforming growth factor beta receptor III; Transforming growth factor beta receptor type 3; transforming growth factor, beta receptor 3; transforming growth factor, beta receptor III
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 21814, 7049
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid