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  4. Invitrogen™ Human TGFBR1 (ALK5), GST Tag Recombinant Protein

Invitrogen™ Human TGFBR1 (ALK5), GST Tag Recombinant Protein

Product Code. 15428713
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Quantity:
1 mg
10 μg
100 μg
Unit Size:
100µg
1mg
Each
This item is not returnable. View return policy

Product Code. 15428713

Brand: Invitrogen™ PR9075A

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This item is not returnable. View return policy

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length.

TGFBR1 is a transmembrane serine/threonine kinase in the TGFBR1 superfamily, which also includes ACVRs and BMPRs. Upon binding TGF-b, TGFBR2 dimerizes with and activates TGFBR1 via phosphorylation leading to downstream phosphorylation of SMADs by TGFBR1. TGFBR1 forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS).
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P36897
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50mM tris with no preservative
Gene ID (Entrez) 7046
Molecular Weight (g/mol) 62.9 kDa
Name Human TGFBR1 (ALK5), GST Tag
Purification Method Purified
Quantity 100 μg
Storage Requirements -80°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias AAT5; activin A receptor type II-like kinase, 53kDa; activin A receptor type II-like protein kinase of 53kD; Activin receptor-like kinase 5; ACVRLK4; ALK5; Alk-5; AU017191; ESK2; ESS1; LDS1; LDS1A; LDS2A; MSSE; mutant transforming growth factor beta receptor I; ser; serine/threonine-protein kinase receptor R4; SKR4; TbetaRI; tbetaR-I; tgf beta receptor 1; TGF-beta receptor type I; TGF-beta receptor type-1; TGF-beta type I receptor; TGFBR1; TGFR1; TGFR-1; Transfor; transforming growth factor beta receptor 1; transforming growth factor beta receptor I; transforming growth factor, beta receptor 1; transforming growth factor, beta receptor I; transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa); transforming growth factor-beta receptor type I
Common Name TGFBR1
Gene Symbol TGFBR1
KinaseFamily STKR Kinase Family
Protein Length 1-503
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag GST-tag
Sequence 1-503
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Kinase Group Ser⁄Thr Kinases: TKL Group
Shipping Condition Dry Ice
Expression System Baculovirus
Protein Family Kinases & Inhibitors
Protein Form Recombinant, Full Length
Form Liquid
Protein Subtype Serine/Threonine Kinases
Research Category Signal Transduction
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