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TG 100801, MedChemExpress

Product Code. 16463618
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Product Code. 16463618 Supplier Medchem Express Supplier No. HY10186

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Description

MedChemExpress TG 100801 is a prodrug that generates TG 100572 by de-esterification in development to treat age-related macular degeneration. TG 100572 is a multi-targeted kinase inhibitor which inhibits receptor tyrosine kinases and Src kinases; has IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 for VEGFR1, VEGFR2, FGFR1, FGFR2, PDGFRβ, Fgr, Fyn, Hck, Lck, Lyn, Src, Yes, respectively.

TG 100801 is a prodrug that generates TG 100572 by de-esterification in development to treat age-related macular degeneration. TG 100572 is a multi-targeted kinase inhibitor which inhibits receptor tyrosine kinases and Src kinases

Specifications

Chemical Name or Material TG 100801
CAS 867331-82-6
Color Red
Purity Grade Notes Research
Molecular Formula C33H30ClN5O3
Quantity 10 mg
Solubility Information DMSO : 5.56 mg/mL (9.58 mM; Need ultrasonic)
SMILES O=C(C1=CC=CC=C1)OC2=CC=C(Cl)C(C3=CC(C)=C(N=C(NC(C=C4)=CC=C4OCCN5CCCC5)N=N6)C6=C3)=C2
Molecular Weight (g/mol) 580.08
Formula Weight 580.08
Percent Purity 95.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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