TfR (Transferrin R) Antibody (TFRC/1817), Novus Biologicals™

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
18295010	Novus Biologicals NBP2-53274-20UG	20 μg
18238880	Novus Biologicals NBP2-53274-100UG	100 μg

Description

TfR (Transferrin R) Monoclonal specifically detects TfR (Transferrin R) in Human samples. It is validated for Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: TfR (Transferrin R)
• Concentration: 0.2 mg/mL
• Applications: Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Mouse
• Research Discipline: Cell Biology, Cellular Markers, Hematopoietic Stem Cell Markers, Immunology, Signal Transduction, Stem Cell Markers
• Formulation: 10mM PBS with 0.05% BSA with 0.05% Sodium Azide
• Gene ID (Entrez): 7037
• Immunogen: Recombinant human extracellular TFRC protein fragment (aa94-212) (exact sequence is proprietary)
• Primary or Secondary: Primary
• Content And Storage: Store at 4C.

• Clone: TFRC/1817
• Dilution: Western Blot 0.5-1.0 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells, ELISA 2 - 4 ug/ml, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 1 - 2 ug/ml, SDS-Page
• Classification: Monoclonal
• Form: Purified
• Regulatory Status: RUO
• Target Species: Human
• Gene Alias: CD71 antigen, CD71TRFR, p90, T9, TfR, TFR1, TR, transferrin receptor (p90, CD71), transferrin receptor protein 1, Trfr
• Gene Symbols: TFRC
• Isotype: IgG2b κ
• Purification Method: Protein A or G purified
• Test Specificity: It recognizes a ∼90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

For Research Use Only