Invitrogen™ TESK2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5110474

Product Code. 17118403

Description

Immunogen sequence: FVEIGKTLEE ILSRLQEEEQ ERDRKLQPTA RGLLEKAPGV KRLSSLDDKI PHKSPCPRRT IWLSRSQSDI FSRKPPRTVS VLDPYYRPRD GAARTPKVNP FSARQDLMGG KIKFFDLPSK SVISLVFDLD APGPGTMPLA DWQEPLAPPI RRWRSLPGSP EFLHQEACPF VGREESLSDG PPPRLSSLKY RVKEIPPFRA SALPAAQAHE AMDCSILQEE NGFGSRPQGT SPCPAGASEE MEVEERPAGS TPATFSTSGI GLQTQGKQDG.

TESK2 or testis-specific kinase 2 is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and belongs to the TESK subgroup of the LIMK/TESK family of protein kinases. The kinase domain of TESK2 is structurally similar to the kinase domain of testis-specific protein kinase-1 and the LIM motif-containing protein kinases (LIMKs). TESK2 is predominantly expressed in testis and prostate and plays an important role in spermatogenesis. TESK2 phosphorylates cofilin specifically at Ser-3 and induces formation of actin stress fibers and focal adhesions.

Specifications

• Antigen: TESK2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TESK2
• Gene Alias: dual specificity testis-specific protein kinase 2; TESK2; Testicular protein kinase 2; testis-specific kinase 2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10420, 230661
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.155 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q8VCT9, Q96S53
• Gene Symbols: TESK2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 302-571 of human TESK2 (NP_009101.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG