Invitrogen™ Tensin 1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA557516

Product Code. 15755411

Description

Immunogen sequence: EEPLNLEGLV AHRVAGVQAR EKQPAEPPAP LRRRAASDGQ YENQSPEATS PRSPGVRSPV QCVSPELALT IALNPGGRPK EPHLHSYK Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 99%.

Tensin is involved in the maintenance of cellular structure by anchoring Actin filaments at the focal adhesion via F-Actin binding and capping activities. However, tensin also contains a Src homology 2 (SH2) domain and has the ability to be phosphorylated. Tensin is phosphorylated on tyrosine, serine, and threonine residues, suggesting that it might participate in signal transduction cascades. These diverse characteristics in a single molecule indicate that tensin may be an important link between the cytoskeleton and signal transduction pathways.

Specifications

• Antigen: Tensin 1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TNS1
• Gene Alias: 1110018I21Rik; 1200014E20Rik; AI648117; DKFZp586K0617; E030018G17Rik; E030037J05Rik; matrix-remodelling associated 6; Matrix-remodelling-associated protein 6; MGC88584; MST091; MST122; MST127; MSTP091; MSTP122; MSTP127; MXRA6; PPP1R155; protein phosphatase 1, regulatory subunit 155; tensin 1; tensin-1; TNS; TNS1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7145
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9HBL0
• Gene Symbols: TNS1
• Immunogen: Recombinant protein corresponding to Human Tensin 1. Recombinant protein control fragment (Product #RP-96507).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG