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Invitrogen™ TEM8 Polyclonal Antibody

Product Code. 12807742
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Quantity:
100 μg
Unit Size:
100µg
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12807742 100 μg 100µg
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Product Code. 12807742 Supplier Invitrogen™ Supplier No. PA520017

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Description

Rabbit Polyclonal Antibody

A suggested positive control is K562 cell lysate. PA5-20017 can be used with blocking peptide PEP-0136.

This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TEM8
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene ANTXR1
Gene Accession No. Q0PMD2, Q9CZ52, Q9H6X2
Gene Alias 2310008J16Rik; 2810405N18Rik; anthrax toxin receptor; anthrax toxin receptor 1; Antrx1; ANTXR1; ATR; FLJ10601; FLJ11298; FLJ21776; GAPO; TEM8; Tem-8; tumor endothelial marker 8
Gene Symbols ANTXR1
Host Species Rabbit
Immunogen A peptide corresponding to 13 amino acids near the C-terminus of human TEM8.
Purification Method Ion-exchange chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 362393, 69538, 84168
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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