Invitrogen™ TEF Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA536187

Product Code. 15507561

Description

This antibody detects endogenous protein at a molecular weight of 33 kDa. Purity is >95% by SDS-PAGE.

TEF (thyrotrophic embryonic factor), also known as KIAA1655, is a 303 amino acid nuclear transcription factor that belongs to the bZIP (basic region/leucine zipper) family and PAR (proline and acidic amino acid-rich) subfamily. TEF binds DNA as either a homodimer or heterodimer, and is known to transactivate the TSH beta promoter. While broadly expressed in adults, TEF is only found in developing embryonic anterior pituitary gland. TEF accumulates according to a robust circadian rhythm and has also been found to inhibit cell growth by downregulating beta chain expression of cytokine receptors. The functional domains of TEF are highly homologous with other members of the PAR-bZIP subfamily, including albumin D box-binding protein (DABP), human hepatic leukemia factor (HLF) and chicken vitellogenin gene-binding protein (VBP).

Specifications

• Antigen: TEF
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TEF
• Gene Alias: 2310028D20Rik; KIAA1655; TEF; TEF, PAR bZIP transcription factor; thyrotroph embryonic factor; thyrotrophic embryonic factor
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 21685, 29362, 7008
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P41224, Q10587, Q9JLC6
• Gene Symbols: TEF
• Immunogen: Synthetic peptide corresponding to amino acids 200-250 of human TEF.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG