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Invitrogen™ TCR V beta F1 Monoclonal Antibody (8A3)

Description
TCR1151 targets TCR Beta F1 in FACS, FISH, IHC, IHC(P), IP, and WB applications and shows reactivity with Human samples. The TCR1151 immunogen is human TCR β chain constant region. TCR1151 detects TCR Beta F1 which has a predicted molecular weight of approximately 13 kDa.
The T Cell Receptor alpha beta (TCRab) is a heterodimeric membrane receptor that consists of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 proteins. TCRab participates in the activation of T-cells in response to an antigen presented in the context of MHC. Engagement of the TCRab initiates signaling cascades that ultimately result in cellular proliferation, differentiation, cytokine production, and/or activation-induced cell death. These signaling cascades regulate T-cell development, homeostasis, activation, acquisition of effector functions and apoptosis. Cells expressing TCRab constitute the vast majority of T cells in both human and mouse.
Specifications
Specifications
| Antigen | TCR V beta F1 |
| Applications | Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot |
| Classification | Monoclonal |
| Clone | 8A3 |
| Concentration | 0.15 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.5% BSA and 0.1% sodium azide |
| Gene | TRB |
| Gene Accession No. | P0DSE2 |
| Gene Alias | T cell receptor beta locus; tcr beta f1; TCRB; TRB; TRB@ |
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Safety and Handling
Product Identifier
- Pierce Purified Antibody(ies)
- Warning
- Acute toxicity Category 4
- H302-Harmful if swallowed.
- P264-Wash hands thoroughly after handling.
- P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
- P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
- MIXTURE LIST-Contains : sodium azide
Product Title
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