TCR β chain Hamster anti-Mouse, PE, Clone: H57-597, BD

Hamster Monoclonal Antibody

Product Code	Brand	Quantity
15880749	BD Biosciences 561081	25 μg
15827058	BD Biosciences 553172	0.1 mg

Description

The H57-597 antibody reacts with a common epitope of the β chain of the T-cell Receptor (TCR) complex on αβ TCR-expressing thymocytes and peripheral T lymphocytes and NK1.1+ thymocytes and NK-T cells of all mouse strains tested. It does not react with γδ TCR-bearing T cells. In the fetal and adult thymus, the TCR β -chain may form homodimers or pair with the pre-TCR α -chain on the surface of immature thymocytes before expression of the TCR α -chain. Plate-bound or soluble H57-597 antibody activates αβ TCR-bearing T cells, and plate-bound mAb can induce apoptotic death.

This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Specifications

• Antigen: TCR β chain
• Concentration: 0.2mg/mL
• Classification: Monoclonal
• Host Species: Hamster
• Target Species: Mouse
• Immunogen: TCR affinity-purified from mouse T-cell hybridoma DO-11.10
• Purification Method: Affinity Purified

• Clone: H57-597
• Applications: Flow Cytometry
• Conjugate: PE
• Regulatory Status: RUO
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

For Research Use Only.