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Invitrogen™ TCP-1 beta Monoclonal Antibody (5B5C4)
Description
MA5-15909 targets CCT2 in indirect ELISA, FACS, IF, and WB applications and shows reactivity with Human, mouse, Non-human primate, and Rat samples. The MA5-15909 immunogen is purified recombinant fragment of human CCT2 expressed in E. Coli. . MA5-15909 detects CCT2 which has a predicted molecular weight of approximately 54kDa.
TCP-1 beta is a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). The CCT complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of the TCP-1 beta gene have been observed but not thoroughly characterized. A disease associated with TCP-1 beta protein dysfunction include epididymo-orchitis.
Specifications
Specifications
| Antigen | TCP-1 beta |
| Applications | ELISA, Flow Cytometry, Western Blot, Immunocytochemistry |
| Classification | Monoclonal |
| Clone | 5B5C4 |
| Concentration | Conc. Not Determined |
| Conjugate | Unconjugated |
| Formulation | ascites with 0.03% sodium azide |
| Gene | CCT2 |
| Gene Accession No. | P78371, P80314, Q5XIM9 |
| Gene Alias | 99D8.1; AI528772; c-cpn; CCT; Cct1; CCT2; Ccta; CCTB; CCT-beta; chaperonin containing t-complex polypeptide 1, beta subunit; chaperonin containing t-complex polypeptide 1, subunit 2; chaperonin containing TCP1 subunit 2; chaperonin containing Tcp1, subunit 2 (beta); chaperonin subunit 2 (beta); chaperonin-containing T-complex polypeptide beta subunit; epididymis secretory sperm binding protein Li 100n; HEL-S-100n; hypothetical protein LOC505313; p63; PRO1633; T-complex protein 1 subunit beta; T-complex protein 1, beta subunit; Tcp-1; TCP-1-beta; Tp63; TRic |
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