TCL1A Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16806883	Proteintech 10475-1-AP-20UL	20 μL
16896873	Proteintech 10475-1-AP-150UL	150 μL

Description

Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha or TCR-beta regulatory elements (summarized by Virgilio et al., 1998). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (Laine et al., 2000).

Specifications

• Antigen: TCL1A
• Applications: Western Blot, Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: P56279
• Gene ID (Entrez): 8115
• Immunogen: TCL1A Fusion Protein Ag0786
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: TCL1A

• Concentration: 0.3 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: Oncogene TCL 1, Oncogene TCL1, Protein p14 TCL1, T cell leukemia/lymphoma 1A, TCL1, TCL1A
• Gene Symbols: TCL1A
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody