Invitrogen™ TCCR Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA599855

Product Code. 16614105

Description

Antibody detects endogenous levels of total IL27RA.

In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells and type 2 (Th2) cells, which are critical for cell-mediated immunity and most antibody responses, respectively. The differentiation of Th1 cells is predominantly under the influence of IL12, while IL4 influences the differentiation of Th2 cells. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but not absent, Th1 or Th2 immune responses. The gene discussed here encodes a protein that is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level and is predicted to be a glycosylated transmembrane protein. Diseases associated with IL27RA include Hyper Ige Recurrent Infection Syndrome 4 and Crisponi/Cold-Induced Sweating Syndrome 2.

Specifications

• Antigen: TCCR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Il27ra
• Gene Alias: class I cytokine receptor; CRL1; CRL1IL-27R; cytokine receptor family, class 1 (WSXWS), member 1; cytokine receptor WSX-1; Cytokine receptor-like 1; il-27 receptor; IL-27 receptor subunit alpha; IL27R; IL-27R; IL-27R subunit alpha; IL27RA; IL-27RA; IL-27R-alpha; interleukin 27 receptor subunit alpha; interleukin 27 receptor, alpha; interleukin-27 receptor subunit alpha; T cell cytokine receptor; T cell cytokine receptor; cytokine receptor family, class 1 (WSXWS), member 1; TCCR; T-cell cytokine receptor type 1; Type I T-cell cytokine receptor; UNQ296/PRO336; WSX1; WSX-1; ZcytoR1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9466
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q6UWB1
• Gene Symbols: Il27ra
• Immunogen: A synthesized peptide derived from human IL27RA(Accession Q6UWB1), corresponding to amino acid residues T30-T80.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG