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TC-DAPK 6, Tocris Bioscience™
Potent and selective inhibitor of DAPK1
£120.63 - £436.03
Chemical Identifiers
| CAS | 315694-89-4 |
|---|---|
| Molecular Formula | C17H12N2O2 |
| Molecular Weight (g/mol) | 276.295 |
| InChI Key | GFGMISOSPOPSHN-QCTDOKRBSA-N |
| Synonym | tc-dapk 6, 4e-2-e-2-phenylethenyl-4-pyridin-3-ylmethylidene-1,3-oxazol-5-one, tc-dapk-6, 2-2-phenylethenyl-4-pyridin-3-ylmethylidene-4,5-dihydro-1,3-oxazol-5-one, 2-2-phenylethenyl-4-pyridin-3-yl methylidene-4,5-dihydro-1,3-oxazol-5-one, 2-styryl-4-3-pyridylmethylene-2-oxazoline-5-one, e-4-pyridin-3-ylmethylene-2-e-styryl oxazol-5 4h-one |
| PubChem CID | 5676111 |
| IUPAC Name | (4E)-2-[(E)-2-phenylethenyl]-4-(pyridin-3-ylmethylidene)-1,3-oxazol-5-one |
| SMILES | C1=CC=C(C=C1)C=CC2=NC(=CC3=CN=CC=C3)C(=O)O2 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18064652
|
Tocris Bioscience
4301/10 |
10 mg |
£120.63
10mg |
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|
18014422
|
Tocris Bioscience
4301/50 |
50 mg |
£436.03
50mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Potent and selective, ATP-competitive inhibitor of death-associated protein kinase 1 (DAPK1) (IC50 values are 69 and 225 nM for DAPK1 and DAPK3 respectively, when assayed with 10 μM ATP). Displays selectivity for DAPK1 over a range of 48 other kinases, including Abl, AMPK, Chk1, Met and Src (IC50 > 10 μM).Chemical Identifiers
| 315694-89-4 | |
| 276.295 | |
| tc-dapk 6, 4e-2-e-2-phenylethenyl-4-pyridin-3-ylmethylidene-1,3-oxazol-5-one, tc-dapk-6, 2-2-phenylethenyl-4-pyridin-3-ylmethylidene-4,5-dihydro-1,3-oxazol-5-one, 2-2-phenylethenyl-4-pyridin-3-yl methylidene-4,5-dihydro-1,3-oxazol-5-one, 2-styryl-4-3-pyridylmethylene-2-oxazoline-5-one, e-4-pyridin-3-ylmethylene-2-e-styryl oxazol-5 4h-one | |
| (4E)-2-[(E)-2-phenylethenyl]-4-(pyridin-3-ylmethylidene)-1,3-oxazol-5-one |
| C17H12N2O2 | |
| GFGMISOSPOPSHN-QCTDOKRBSA-N | |
| 5676111 | |
| C1=CC=C(C=C1)C=CC2=NC(=CC3=CN=CC=C3)C(=O)O2 |
Specifications
| 315694-89-4 | |
| tc-dapk 6, 4e-2-e-2-phenylethenyl-4-pyridin-3-ylmethylidene-1,3-oxazol-5-one, tc-dapk-6, 2-2-phenylethenyl-4-pyridin-3-ylmethylidene-4,5-dihydro-1,3-oxazol-5-one, 2-2-phenylethenyl-4-pyridin-3-yl methylidene-4,5-dihydro-1,3-oxazol-5-one, 2-styryl-4-3-pyridylmethylene-2-oxazoline-5-one, e-4-pyridin-3-ylmethylene-2-e-styryl oxazol-5 4h-one | |
| C1=CC=C(C=C1)C=CC2=NC(=CC3=CN=CC=C3)C(=O)O2 | |
| 276.295 | |
| 276.29 | |
| TC-DAPK 6 |
| C17H12N2O2 | |
| GFGMISOSPOPSHN-QCTDOKRBSA-N | |
| (4E)-2-[(E)-2-phenylethenyl]-4-(pyridin-3-ylmethylidene)-1,3-oxazol-5-one | |
| 5676111 | |
| >98% |
Safety and Handling
Recommended Storage : Store at +4°C