Invitrogen™ TBC1D17 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA570937

Product Code. 15879343

Description

This target displays homology in the following species: Cow: 93%; Dog: 93%; Goat: 80%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Rat: 93%; Zebrafish: 77%.

Probable GTPase-activating protein for Rab8; its transient association with Rab8 is mediated by OPTN. Inhibits Rab8-mediated endocytic trafficking, such as of transferrin receptor (TfR) and reduces Rab8 recruitnment to tubules emanating from the endocytic recycling compartment (ERC). Involved in regulation of autophagy. Mediates inhibition of autophagy caused by the OPTN variant GLC1E LYS-50; the function requires its catalytic activity, however, the involved Rab is not known. [UniProt].

Specifications

• Antigen: TBC1D17
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TBC1D17
• Gene Alias: BC017607; hypothetical protein LOC554092; TBC1 domain family member 17; TBC1 domain family, member 17; TBC1D17; wu:fc56c02; zgc:110443; zgc:110443 protein
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 233204
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q8BYH7
• Gene Symbols: TBC1D17
• Immunogen: synthetic peptide directed towards the middle region of mouse TBC1D17.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG