Invitrogen™ TAZ Monoclonal Antibody (2B3)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA520076

Product Code. 15548862

Description

Peptide Sequence: MPLHVKWPFP AVPPLTWTLA SSVVMGLVGT YSCFWTSEWA QAEAGPPGYP CPAGGILKLR HIWNLKLMRW TPAAADICFT KELHSHFFSL GKCVPVCRGD GVYQKGMDFI LEKLNHGDWV HIFPEGIGRL IAECHLNPII LPLWHVGEPG DGDREMASGV GGLGLPLVPG CPAPPHVWPS VHCAAGMNDV LPNSPPYFPR FGQKITVLIG KPFSALPVLE RLRAENKSAV EMRKALTDFI QEEFQHLKTQ AEQLHNHLQP GR.

This gene encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in this gene have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy, hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction. Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is produced; the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternatively spliced transcripts have been described but the full-length nature of all these transcripts is not known.

Specifications

• Antigen: TAZ
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q16635
• Gene Symbols: TAZ
• Immunogen: TAZ (AAH11515, 1 a.a. ~ 262 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: ELISA, Western Blot
• Clone: 2B3
• Conjugate: Unconjugated
• Gene: TAZ
• Gene Alias: 2310058J06Rik; 2610021I22Rik; 5031411C02Rik; 9130012G04Rik; AW107266; AW552613; Barth syndrome); BTHS; C78399; cardiomyopathy, dilated 3A (X-linked); CMD3A; EFE; EFE2; endocardial fibroelastosis 2; FLJ27390; G4.5; HGNC:11577; LVNCX; OTTHUMP00000061673; protein G4.5; Tafazzin; tafazzin (cardiomyopathy, dilated 3A (X-linked); tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome); Taz; Taz1; transcriptional coactivator with PDZ binding motif; transcriptional co-activator with PDZ-binding motif; transcriptional coactivator with PDZ-binding motif; transcriptional co-activator with PDZ-binding motif (TA)Z; transcriptional co-activator with PDZ-binding motif (TAZ); WW domain containing transcription regulator 1; WW domain-containing transcription regulator protein 1; Wwtr1; XAP-2; XX-FW83563B9.3
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 363521, 6901
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid