Invitrogen™ Tavolixizumab Recombinant Monoclonal Antibody

Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA558737

Product Code. 30283057

Description

For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °.

Tavolixizumab, also known as Tyenne® (tocilizumab-aazg), is a biosimilar to Actemra® (tocilizumab), an Interleukin-6 (IL-6) receptor antagonist. Tavolixizumab targets the IL-6 receptor, thereby inhibiting the IL-6 signaling pathway, which plays a crucial role in the inflammatory response associated with autoimmune diseases such as rheumatoid arthritis and systemic juvenile idiopathic arthritis. The biosimilar is available in various formulations, including prefilled syringes, pen injectors, and vials for subcutaneous and intravenous administration, providing versatile treatment options. Tavolixizumab has demonstrated efficacy and safety comparable to the reference product, with serious infections being one of the noted adverse effects. Synonyms for Tavolixizumab include tocilizumab-aazg and Tyenne.

Specifications

• Antigen: Tavolixizumab Humanized
• Classification: Recombinant Monoclonal
• Conjugate: Unconjugated
• Host Species: Human
• Quantity: 100 μg
• Primary or Secondary: Primary
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: ELISA, Flow Cytometry, Functional Assay, Surface Plasmon Resonance
• Concentration: 1 mg/mL
• Formulation: 25mM histidine with 8% sucrose, 0.01% Tween 80 and no preservative; pH 6.2
• Purification Method: Protein A
• Regulatory Status: RUO
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1