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TAS6417, MedChemExpress

Product Code. 16495456
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Product Code. 16495456 Supplier Medchem Express Supplier No. HY112299

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Description

MedChemExpress TAS6417 (CLN-081) is a highly effective, orally active and pan-mutation-selective EGFR tyrosine kinase inhibitor with a unique scaffold fitting into the ATP-binding site of the EGFR hinge region, with IC50 values ranging from 1.1-8.0 nM.

TAS6417 (CLN-081) is a highly effective, orally active and pan-mutation-selective EGFR tyrosine kinase inhibitor with a unique scaffold fitting into the ATP-binding site of the EGFR hinge region, with IC50 values ranging from 1.1-8.0 nM.

Specifications

Chemical Name or Material TAS6417
CAS 1661854-97-2
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C23H20N6O
Quantity 100 mg
Synonym CLN-081
Solubility Information DMSO : 22.73 mg/mL (57.34 mM; Need ultrasonic)
SMILES NC1=C2C(N3C(C(C)=C[C@@H](C3)NC(C=C)=O)=C2C4=CC5=CC=CC=C5N=C4)=NC=N1
Molecular Weight (g/mol) 396.44
Formula Weight 396.44
Percent Purity 97.63%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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