Invitrogen™ TAS2R41 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA563394

Product Code. 15721172

Description

Immunogen sequence: NFYYSAQKVE YSGGLGRQFF H Highest antigen sequence identity to the following orthologs: Mouse - 52%, Rat - 52%.

TAS2R41 is a receptor that may play a role in the perception of bitterness and belongs to the G-protein receptor superfamily. TAS2R41 is expressed mainly in taste receptor cells of the tongue and the palate eptithelia. Structurally, the TAS2R41 gene encodes a seven trans-membrane receptor protein and is clustered together with eight other taste receptor genes on chromosome 7. The compound chloramphenicol is an agonist for the TAS2R41 protein. Further, TAS2R41 may play a role in sensing the chemical composition of the gastrointestinal content. The activity of TAS2R41 may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. TAS2R41 is expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.

Specifications

• Antigen: TAS2R41
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TAS2R41
• Gene Alias: MGC119928; MGC119929; mGR26; mt2r35; T2R12; T2R26; T2R41; T2R59; Tas2r12; Tas2r126; Tas2r26; Tas2r41; taste 2 receptor member 41; taste receptor rT2R12; taste receptor type 2 member 41; Taste receptor type 2 member 59; taste receptor, type 2, member 126; taste receptor, type 2, member 41
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 259287, 266656
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P59536
• Gene Symbols: TAS2R12P, TAS2R41
• Immunogen: Recombinant protein corresponding to Human TAS2R41. Recombinant protein control fragment (Product #RP-101629).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG