Invitrogen™ TAS2R16 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5102251

Product Code. 16658724

Description

Antibody detects endogenous levels of total TAS2R16.

This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily. These family members are specifically expressed by taste receptor cells of the tongue and palate epithelia. Each of these apparently intronless genes encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception. Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Expressed in a subset of gustducin-positive taste receptor cells of the tongue. The Lys-172 polymorphism in TAS2R16 is associated with genetic susceptibility to alcoholism. Confers bitter perception of salicin to non-taster mice.

Specifications

• Antigen: TAS2R16
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TAS2R16
• Gene Alias: candidate taste receptor T2R16; T2R16; TAS2R16; taste 2 receptor member 16; taste receptor type 2 member 16; taste receptor, type 2, member 16
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 50833
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9NYV7
• Gene Symbols: TAS2R16
• Immunogen: A synthesized peptide derived from human TAS2R16(Accession Q9NYV7), corresponding to amino acid residues I142-F192.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG