Tapasin Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Thermo Scientific PA552382

Product Code. 15770331

Description

Immunogen sequence: QEGTYLATIH LPYLQGQVTL ELAVYKPPKV SLMPATLARA APGEAPPELL CLVSHFYPSG GLEVEWELRG GPGGRSQKAE GQRWLSALRH HSDGSVSLSG HLQPPPVTTE QHGARYACRI HHPS Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 77%.

This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.

Specifications

• Antigen: Tapasin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TAPBP
• Gene Alias: D17Wsu91e; DADB-159G18.7; NGS17; NGS-17; similar to Tapasin precursor (TPSN) (TPN) (TAP-binding protein) (TAP-associated protein) (NGS-17); TAP binding protein; TAP binding protein (tapasin); TAPA; tapasin; TAP-associated protein; TAP-binding protein; Tapbp; TPN; TPSN
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6892
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O15533
• Gene Symbols: TAPBP
• Immunogen: Recombinant protein corresponding to Human Tapasin
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Research Use Only