Invitrogen™ Tapasin Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA542731

Product Code. 15565642

Description

Peptide sequence: GEAPPELLCL VSHFYPSGGL EVEWELRGGP GGRSQKAEGQ RWLSALRHHS Sequence homology: Cow: 86%; Human: 100%; Pig: 86%; Sheep: 86%.

This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.

Specifications

• Antigen: Tapasin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TAPBP
• Gene Alias: D17Wsu91e; DADB-159G18.7; NGS17; NGS-17; similar to Tapasin precursor (TPSN) (TPN) (TAP-binding protein) (TAP-associated protein) (NGS-17); TAP binding protein; TAP binding protein (tapasin); TAPA; tapasin; TAP-associated protein; TAP-binding protein; Tapbp; TPN; TPSN
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6892
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: O15533
• Gene Symbols: TAPBP
• Immunogen: Synthetic peptide directed towards the C-terminal of human TAPBP (aa 307-356).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG