TAOK2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16830815	Proteintech 21188-1-AP-20UL	20 μL
16820815	Proteintech 21188-1-AP-150UL	150 μL

Description

The immunogen of this antibody is 742-969 aa of human TAOK2 protein isoform Alpha. This antibody mainly detects the isoforms 1, 3, and 4. It does not detect isoform 2.

In vitro, TAO (thousand and one amino acid) protein kinase 2 (TAO2) activates MAP/ERK kinases (MEK ) 3, 4, and 6 toward their substrates p38 MAP kinase JNK/SAPK (Chen et al., 1999; Chen and Cobb, 2001). This and more recent work has led to the proposal that the TAO protein kinases play an essential role in signaling from physiological agonist to the stress -responsive p38 MAPK (Chen et al., 2003). Autophosphorylation of TAO may play a role in the mechanism of TAO activation. The MEK binding domain of TAO is autophosphorylated on both serine and threonine residues and Ser181 is located within this domain.

Specifications

• Antigen: TAOK2
• Applications: Western Blot, Immunoprecipitation
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Rat, Mouse, Human
• Gene Accession No.: Q6ZQ29, Q9JLS3, Q9UL54
• Gene ID (Entrez): 381921, 64666, 9344
• Immunogen: TAOK2 Fusion Protein Ag15521
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: TAOK2

• Concentration: 0.26 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: hKFC C, KIAA0881, Kinase from chicken homolog C, MAP3K17, PSK, PSK 1, PSK1, TAO kinase 2, TAO1, TAO2, TAOK2
• Gene Symbols: Taok2
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody