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  6. Invitrogen™ TAOK1 Recombinant Rabbit Monoclonal Antibody (K01_2P66)

Invitrogen™ TAOK1 Recombinant Rabbit Monoclonal Antibody (K01_2P66)

Product Code. 30828126
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30828126 50 μL
30826341 100 μL
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Product Code. 30828126 Supplier Invitrogen™ Supplier No. MA565674
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Estimated Shipment: 09-09-2026
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Description

Rabbit Recombinant Monoclonal Antibody

TAOK1 Recombinant Monoclonal Antibody for Western Blot

TAOK1 is a serine/threonine-protein kinase involved in regulation of the p38-containing stress-responsive MAP kinase pathway and extracellular signal-regulated protein kinase (ERK) kinases (MEKs). The activation of and binding to MEK3 by TAOK1 implicates TAOK1 in the regulation of the p38-containing stress-responsive MAP kinase pathway. A microtubule affinity-regulating kinase, TAOK1 (also known as MARKK) is an important regulator of mitotic progression, required for both chromosome congression and checkpoint-induced anaphase delay. TAOK1 is involved in various processes such as p38/MAPK14 stress-activated MAPK cascase, DNA damage response, and regulations of cytoskeleton stability. It phosphorylates MAP2K3, MAP2K6, and MARK2. TAOK1 acts as an activator of the p38/MAPK cascade by mediating phosphorylation and subsequent activation of the upsteam MAP2K3 and MAP2K6 kinases. It is involved in G-protein couples receptor signaling to p38/MAPK14. In response to DNA damage, TAOK1, is involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade by phosphorylaton of MAP2K3 and MAP2K6. In addition, it acts as a regulator of cytoskeleton stability and a regulator of apoptosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TAOK1
Applications Western Blot
Classification Recombinant Monoclonal
Clone K01_2P66
Concentration 0.90 mg/mL
Conjugate Unconjugated
Formulation 50mM tris glycine with 40% glycerol, 0.05% BSA, 150mM NaCl and 0.01% sodium azide; pH 7.4
Gene TAOK1
Gene Accession No. O88664, Q5F2E8, Q7L7X3
Gene Alias 2810468K05Rik; AU020252; D130018F14Rik; FLJ14314; h hTAOK1; H KIAA1361; hKFC-B; hTAOK1; KFC-B; Kiaa1361; Kinase from chicken homolog B; MAP3K16; MARK Kinase; Markk; microtubule affinity regulating kinase kinase; mKIAA1361; prostate-derived STE20-like kinase 2; prostate-derived sterile 20-like kinase 2; PSK2; PSK-2; serine/threonine protein kinase TAO1; serine/threonine protein kinase TAO1 homolog; serine/threonine-protein kinase TAO1; STE20-like kinase PSK2; tao; TAO kinase 1; TAO1; TAOK1; Thousand and one amino acid protein 1; thousand and one amino acid protein kinase 1
Gene Symbols TAOK1
Host Species Rabbit
Immunogen A synthetic peptide of human TAOK1.
Purification Method Protein A/G
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 216965, 286993, 57551
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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