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Talmapimod, MedChemExpress

Product Code. 16443948
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Product Code. 16443948 Supplier Medchem Express Supplier No. HY10406

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Description

MedChemExpress Talmapimod (SCIO-469) is an orally active, selective, and ATP-competitive p38α inhibitor with an IC50 of 9 nM. Talmapimod shows about 10-fold selectivity over p38β, and at least 2000-fold selectivity over a panel of 20 other kinases, including other MAPKs.

Talmapimod (SCIO-469) is an orally active, selective, and ATP-competitive p38α inhibitor with an IC50 of 9 nM. Talmapimod shows about 10-fold selectivity over p38β, and at least 2000-fold selectivity over a panel of 20 other kinases, including other MAPKs.

Specifications

Chemical Name or Material Talmapimod
CAS 309913-83-5
Color Pink
Purity Grade Notes Research
Molecular Formula C27H30ClFN4O3
Quantity 10 mg
Synonym SCIO-469
Solubility Information DMSO : ≥ 100 mg/mL (194.93 mM)
SMILES O=C(N(C)C)C(C1=CN(C)C2=C1C=C(C(N3[C@H](C)CN(CC4=CC=C(F)C=C4)[C@@H](C)C3)=O)C(Cl)=C2)=O
Molecular Weight (g/mol) 513.0
Formula Weight 513.0
Percent Purity 98.04%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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