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TAK-220, MedChemExpress

Product Code. 16473917
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16473917 50 mg 50mg
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16417776 100 mg 100mg
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Product Code. 16473917 Supplier Medchem Express Supplier No. HY19974

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Description

MedChemExpress TAK-220 is a selective and orally bioavailable CCR5 antagonist, with IC50s of 3.5 nM and 1.4 nM for inhibition on the binding of RANTES and MIP-1α to CCR5, respectively, but shows no effect on the binding to CCR1, CCR2b, CCR3, CCR4, or CCR7

TAK-220 also selectively inhibits HIV-1, with EC50s of 1.2 nM (HIV-1 KK), 0.72 nM (HIV-1 CTV), 1.7 nM (HIV-1 HKW), 1.7 nM (HIV-1 HNK), 0.93 nM (HIV-1

Specifications

Chemical Name or Material TAK-220
CAS 333994-00-6
Color Off-White
Purity Grade Notes Research
Molecular Formula C31H41ClN4O3
Quantity 50 mg
Solubility Information DMSO : ≥ 50 mg/mL (90.39 mM)
SMILES O=C(C1CCN(C(C)=O)CC1)N(CCCN2CCC(CC3=CC=C(C(N)=O)C=C3)CC2)C4=CC=C(C)C(Cl)=C4
Molecular Weight (g/mol) 553.14
Formula Weight 553.14
Percent Purity 99.9%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-anti-virus
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Research purposes only

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