TAF15 Mouse anti-Human, Clone: 4D71, Abnova™

Mouse monoclonal antibody raised against full length recombinant human TAF15.

Brand:  Abnova MAB12500.50uL

Product Code. 16061116

Description

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a subunit of TFIID present in a subset of TFIID complexes. Translocations involving chromosome 17 and chromosome 9, where the gene for the nuclear receptor CSMF is located, result in a gene fusion product that is an RNA binding protein associated with a subset of extraskeletal myxoid chondrosarcomas. Two transcripts encoding different isoforms have been identified. [provided by RefSeq]

Specifications

• Antigen: TAF15
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Immunofluorescence (1:500-1:1000) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) Western Blot (1:1000) The optimal working dilution should be determined by the end user.
• Gene Alias: Npl3/RBP56/TAF2N/TAFII68/hTAFII68
• Host Species: Mouse
• Purification Method: Protein G purification
• Regulatory Status: RUO
• Gene ID (Entrez): 8148
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1 κ

• Applications: Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
• Clone: 4D71
• Description: Mouse monoclonal antibody raised against full length recombinant human TAF15.
• Formulation: In PBS (0.05% sodium azide)
• Gene Symbols: TAF15
• Immunogen: Recombinant protein corresponding to full length of human TAF15.
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid