Invitrogen™ TADA3L Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA596535

Product Code. 16569371

Description

Immunogen sequence: EENIISPMED SPIPDMSGKE SGADGASTSP RNQNKPFSVP HTKSLESRIK EELIAQGLLE SEDRPAEDSE DEVLAELRKR QAELKALSAH NRTKKHDLLR; Positive Samples: HT-29, BxPC-3, HepG2, HeLa, Mouse testis, Mouse liver, Rat testis, Rat liver; Cellular Location: Nucleus.

Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined.

Specifications

• Antigen: TADA3L
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TADA3
• Gene Alias: 1110004B19Rik; ADA3; ADA3 homolog; ADA3-like protein; AI987856; alteration/deficiency in activation 3; fa03f04; FLJ20221; FLJ21329; hADA3; mADA3; NGG1; STAF54; Tada3; Tada3l; Transcriptional adapter 3; transcriptional adapter 3-like; transcriptional adaptor 3; transcriptional adaptor 3 (NGG1 homolog, yeast)-like; transcriptional adaptor 3-like isoform b; Unknown (protein for MGC:133915); wu:fa03f04; zgc:63596
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 101206, 10474, 362414
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 0.59 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O75528, Q4V8F5, Q8R0L9
• Gene Symbols: TADA3
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 270-369 of human TADA3 (NP_5978141).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG