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T Cell Receptor Gamma/Delta Hamster, anti-Mouse, APC, Clone: GL3, STEMCELL Technologies
Hamster Monoclonal Antibody
£166.05 - £469.80
Specifications
Antigen | T Cell Receptor Gamma/Delta |
---|---|
Clone | GL3 |
Applications | Immunohistochemistry, Flow Cytometry, Immunofluorescence, Functional Assay, Blocking Assay |
Classification | Monoclonal |
Conjugate | APC |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
17189021
|
Stemcell Technologies
60104AZ.1 |
25 μg |
£166.05
25µg |
Estimated Shipment: 05-06-2024 Log in to see stock. |
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17179021
|
Stemcell Technologies
60104AZ |
100 μg |
£469.80
100µg |
Estimated Shipment: 05-06-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
- The GL3 antibody reacts with the δ chain of the murine T cell receptor γ/δ (TCRγ/δ or TCR gamma/delta), a subtype of the TCR involved in the recognition of both peptide and lipid antigens
- TCRγ/δ comprises a heterodimer (∼ 80 kDa in humans) of disulfide-linked γ and δ subunits that associates with CD3 on the cell surface
- It is a member of the immunoglobulin superfamily
- TCRγ/δ is expressed on a subpopulation of T cells in the circulation but may be found on up to 50% of the T cells in epithelial cell-rich tissues
- These cells have roles in oral and tumor-associated tolerance as well as autoimmune disease and have been described as a link between the adaptive and innate immune responses
- Once activated, they secrete effector cytokines in a subtype- and context-specific manner
- Most γ/δ T cells are CD4-/CD8-, though some express CD8
- The GL3 antibody recognizes an epitope in the constant region of the δ chain and can reportedly activate TCRγ/δ+ cells
Specifications
T Cell Receptor Gamma/Delta | |
Immunohistochemistry, Flow Cytometry, Immunofluorescence, Functional Assay, Blocking Assay | |
APC | |
Mouse | |
Primary |
GL3 | |
Monoclonal | |
Hamster | |
IgG2 κ |